Exosomes increase PD-L1 expression and induce tolerance to NIMA

A University of WI Madison research group used Ancell antibodies to analyze exosomes involved in the induction of tolerance to non-inherited maternal antigens(NIMA). This could have implications for allogeneic graft tolerance./

“Cross-Decoration of Dendritic Cells by Non-Inherited Maternal Antigen-Containing Extracellular Vesicles: Potential Mechanism for PD-L1-Based Tolerance in Cord Blood and Organ Transplantation”Diego A. Lema, A Sullivan, et al.Am J Transplant First published: 10 February 2022DOI: 10.1111/ajt.16970 PMID: 35143105

Related Ancell anti-human antibodies:


Recombinant human CD279(PD-1)-muIg

anti-tetraspan Biotinylated mAbs for exosome analysis