CD56(trn)-muIg Biotinylated

Human CD56 is an adhesion molecule from the Ig superfamily which is restricted to NK cells in the immune system.  It is believed that NK cells form a first line of defense against tumor cells and cells infected with bacteria and viruses.

Molecular Structure: A soluble fusion protein consisting of the extracellular  loop domains 1-4  (370aa) of human CD56 (20)LQVDIV….CTASN(389)

fused to murine IgG2a Fc and hinge (232aa), with a predicted monomeric molecular weight of  kd 67.8.

Transfectant Cell Line: CHO

Functional Application: CD56(trn)-muIg fusion protein blocks binding of anti-human CD56 antibody (cat #308-020, but not cat #208-020) to NK cells present in ficoll prepared human PBL.

References:

S.P. Bourne, et al, (1991) J Neuro-Oncol  10: 111-119. T.L. Whiteside and R.B. Herberman (1994) Clinical & Diagnostic Laboratory  Immunology.  H. Spits, et al, (1995) Blood  85: 2654-2670.

USD $425.00
In cart: 0
= $425.00
Catalog #:
522-030
Form:
Biotin
Size:
25 µg
Alternate Name:
NCAM
Applications:
EIA

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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