Human CD56 is an adhesion molecule from the Ig superfamily which is restricted to NK cells in the immune system. It is believed that NK cells form a first line of defense against tumor cells and cells infected with bacteria and viruses.
Molecular Structure: A soluble fusion protein consisting of the extracellular loop domains 1-4 (370aa) of human CD56 (20)LQVDIV….CTASN(389)
fused to murine IgG2a Fc and hinge (232aa), with a predicted monomeric molecular weight of kd 67.8.
Transfectant Cell Line: CHO
S.P. Bourne, et al, (1991) J Neuro-Oncol 10: 111-119. T.L. Whiteside and R.B. Herberman (1994) Clinical & Diagnostic Laboratory Immunology. H. Spits, et al, (1995) Blood 85: 2654-2670.