Human CD69 is expressed by platelets and mature thymocytes and appears rapidly after activation on T cells, B cells and NK cells. This pattern of cellular CD69 expression has suggested a lymphocyte activation role. Functional studies with antibodies to CD69 also support an activation role for CD69 (1, 2).
Isotype: Murine IgG2a
Immunogen: IL-2 activated human NK cells
Specificity: Antibody HP-4B3 recognizes the dimeric CD69 molecule of 60 kd.
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3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1123-1132.
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6) K Wang, X Li, et al. (2017) Int J Clin Exp Pathol 10(5): 5538-5544.