anti-CD69 Biotinylated

Human CD69 is expressed by platelets and mature thymocytes and appears rapidly after activation on T cells, B cells and NK cells.  This pattern of cellular CD69 expression has suggested a lymphocyte activation role.  Functional studies with antibodies to CD69 also support an activation role for CD69 (1, 2).

Isotype: Murine IgG2a

Immunogen: IL-2 activated human NK cells

Specificity: Antibody HP-4B3 recognizes the dimeric CD69 molecule of 60 kd.

References:

1.  S.F. Ziegler, et al, (1994) Stem Cells  12: 456-465.

2.  R. Testi, et al, (1994) Immunol Today  15: 479-483.

3.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1123-1132.

4. D. Vanhecke, et al, (1995) J Immunol  155: 1862-1872.

5. L Chiossone, C Bottino, et al. (2016) Stem Cells 34(7): 1909-21. PMID: 27015881

6) K Wang, X Li, et al. (2017) Int J Clin Exp Pathol 10(5): 5538-5544.

USD $235.00
In cart: 0
= $235.00
Catalog #:
221-030
Form:
Biotin
Size:
100 µg
Alternate Name:
AIM
Clone:
HP-4B3
Applications:
FC(5)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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