anti-CD29 FITC Conjugate
Human CD29 is the beta subunit of an integrin family of molecules expressed on diverse cell types which function as the major receptors for extracellular matrix and as cell-cell adhesion molecules. CD29 can form heterodimer pairs with at least nine different alpha subunits (1).
Isotype: Murine IgG1kappa
Immunogen: Human ocular melanoma cell line, V+B2
Specificity: Antibody 4B7R recognizes the CD29 integrin subunit. It has been reported to work in Western blot under non reducing conditions at a concentration of 1-2 μg/ml. It has also been reported to cross react with Porcine and Mouse CD29.
References:
1. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1612-1613.
2. C M Michelo, I Joosten, et al. (2016) Transplant Immunology 37: 1-9. PMID: 27142560
3. O Trubiani, G Ramazotti, et al. (2016) Cell Signal 28(11): 1631-1641 PMID: 27478064