Human CD29 is the beta subunit of an integrin family of molecules expressed on diverse cell types which function as the major receptors for extracellular matrix and as cell-cell adhesion molecules. CD29 can form heterodimer pairs with at least nine different alpha subunits (1).
Isotype: Murine IgG1kappa
Immunogen: Human ocular melanoma cell line, V+B2
Specificity: Antibody 4B7R recognizes the CD29 integrin subunit. It has been reported to work in Western blot under non reducing conditions at a concentration of 1-2 μg/ml. It has also been reported to cross react with Porcine and Mouse CD29.
1. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1612-1613.
2. C M Michelo, I Joosten, et al. (2016) Transplant Immunology 37: 1-9. PMID: 27142560
3. O Trubiani, G Ramazotti, et al. (2016) Cell Signal 28(11): 1631-1641 PMID: 27478064