anti-CD10 FITC Conjugate

Human CD10 is a well known marker for common acute lymphoblastic leukemia antigen (CALLA) (4).  CD10 is expressed on normal early B cells in bone marrow and is also on fetal thymocytes.  CD10 expression is lost as the T and B lineage cells mature and only appears again on activated germinal center B cells.  CD10 is present on neutrophils.  CD10 is a neutral endopeptidase and hydrolyzes peptide bonds on the amino side of hydrophobic amino acids.

Isotype: Murine IgG1kappa

Immunogen: Membrane preparation of human B-lineage leukemia cells

Specificity: Antibody SN5c recognizes an extracellular epitope of the the human 100 kd membrane-associated peptidase CD10 (1, 2, 3).

References:

1.  H. Matsuzaki, et al, (1987) Cancer Research  47: 2160-2166.

2.  W.C. Biddle, et al, (1989) Leukemia Research  13: 699-707.

3.  H. Hara, et al, (1988) Cancer Research  48: 4673-4680.

4. Leukocyte Typing V (S.F. Schlossman, et al, eds.)  Oxford University Press, Oxford, (1995)  p. 505-507.

USD $235.00
In cart: 0
= $235.00
Catalog #:
157-040
Form:
FITC
Size:
120 tests
Alternate Name:
CALLA, gp100, NEP, MME, Membrane metallo-endopeptidase,
Clone:
SN5c/L4-1A1
Applications:
FC, WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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