anti-CD9 FITC Conjugate

Human CD9 is strongly expressed on platelets, on early B cells and on activated T cells.  CD9 is a member of the tetraspan family crossing the membrane four times (2).  Both the N-terminal and C-terminal regions are on the cytoplasmic side of the plasma membrane.  Recent studies indicate CD9 may be involved with calcium mobilization (3).

Isotype: Murine IgG1 kappa

Immunogen: Membrane antigen preparation of NALM-6 (human pre-B leukemia cell line)

Specificity: Antibody SN4 recognizes the Large Extracellular Domain (LED) (4) of human tetraspan CD9 molecule of about 24 kd (1).

References:

1.  Y. Luo, et al, (1989) Cancer Research  49: 706-710.

2.  F. Lanza, et al, (1991) J Biol Chem  266: 10638-10645.

3.  K. Kuroda, et al, (1995) J Immunol  155: 4427-4436.

4. G.L. Dale, G. Remenyi, P. Friese (2009) Platelets 20(6): 361-366. PMID: 19658001

5. K. Kimura, T. Yamamura, et al. (Jan 2018)9 Nat Commun 9: 17. doi: 10.1038/s41467-017-02406-2 PMID: 29295981

USD $300
In cart: 0
= $300
Catalog #:
156-040
Form:
FITC
Size:
120 tests
Alternate Name:
MRP-1
Clone:
SN4/C3-3A2
Applications:
FC, WB(5)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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