anti-CD1b FITC Conjugate

The human CD1 genetic locus consists of five closely related genes (1).  Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional antigen presenting cells (2).  CD1 molecules have a specialized lipid antigen-presenting function (3).

Isotype: Murine IgG1 kappa

Immunogen: Membrane antigen preparation of human thymocytes

Specificity: Antibody SN13 is specific for the CD1b molecule of about 45 kd.  Specificity was confirmed using CD1b transfectants.

References:

1.  Leukocyte Typing III (A.J. McMichael, et al, eds.)  Oxford University Press, Oxford, (1987) p. 882.

2.  Leukocyte Typing V (S.F. Schlossman, et al, eds.)  Oxford University Press, Oxford, (1995) p. 337-341.

3.  E.M. Beckman, et al, (1994) Nature 372(6507): 691-694.

4.  S M Hayes,  K L Knight (2001) J Immunol 166(1): 403-410

USD $235.00
In cart: 0
= $235.00
Catalog #:
142-040
Form:
FITC
Size:
120 tests
Clone:
SN13
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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