anti-mouse CD4 PE-Cy7

Antibody GK1.5 binds to an extracellular epitope of the 55kd CD4 molecule present on a murine T cell subset (1,2).  CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T Cell Receptor signaling.  This clone has proven effective as a T cell depletion reagent(3).

Isotype:  Rat IgG2bk

Immunogen:    Mouse CTL-V4 membrane prep

 

References:

1) Wilde DB, Fitch FW, et al. (1983) J Immunol 131(5):2178-2183.

2) Dialynas DP, Fitch FW, et al. (1983) J Immunol 131(5):2445-2451.

3) Mochimaru H, Ishida S, et al. (2008) Invest Ophthamol Vis Sci 49(5):2172-2177.

4) Vernooy J H J, E F M Wouters, et al. (2002) Am J Respir Cell Mol Biol 26: 152-159.  PMID:11751215

USD $350.00
In cart: 0
= $350.00
Catalog #:
704-070
Form:
PE-Cy7
Size:
120 tests
Clone:
GK1.5
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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