anti-CD133 Allophycocyanin

 Human CD133 is a 117kd pentaspan transmembrane glycoprotein expressed by a subset of hematopoetic and other types of stem cells found in blood and a variety of tissues. Increased expression of CD133 may be a predictor of decreased prognosis in patients with metastatic cancer(3).

Isotype: Mouse IgG1k

Immunogen: WERI-Rb-1 retinoblastoma

Specificity: Antibody ANC9C5 recognizes epitope 1 of human CD133(AC133) present on full length CD133 transfectants, Y-79 retinoblastoma, and other cell types.

Functional Application:  Antibody ANC9C5 has been used to image cancer stem cells in a colon carcinoma xenograft (4).

References:

1) Miraglia S, Buck DW, et al. (1997) Blood 90(12): 5013-5021.

2) Shmelkov SV, Rafii S, et al. (2005) Int J Biochem Cell Biol 37(4): 715-9.

3) Mehra N, Voest EE, et al. (2006) Clin Canc Res 12(16): 4859-66.

4) Jin ZH, Fuibayashi Y, et al. (2012) Mol Imaging 11: 445-50. PMID: 23084245.

USD $350.00
In cart: 0
= $350.00
Catalog #:
363-060
Form:
APC
Size:
120 tests
Alternate Name:
AC133, Prominin, PROML1, PROM1
Clone:
ANC9C5
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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