anti-CD49f R-PE Conjugate

Human CD49f molecules are integrin alpha 6 chains that are expressed as heterodimers with CD29 (beta 1 integrin) or CD104 (beta 4 integrin) and function as adhesion receptors.  CD49f is expressed on platelets, monocytes, T lymphocytes and thymoctyes.  The ligands for CD49f/CD29 include laminin and invasion.  CD49f/CD29 has been shown to associate with CD63 (3).

Isotype: Murine IgG1

Immunogen: UM-UC-9, human bladder cancer cells

Specificity: Antibody BQ16 recognizes the CD49f molecule of about 150 kd (1, 2).

References:

1.  M. Liebert, et al, (1993) Hybridoma  12: 67-80.

2.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1619-1620.

3.  F. Berditchevski, et al, (1995) J Biol Chem  270: 17784-17790

USD $300.00
In cart: 0
= $300.00
Catalog #:
356-050
Form:
R-PE
Size:
120 tests
Alternate Name:
VLA-6, Integrinα6
Clone:
BQ16
Applications:
FC, IHC(1), WB(1

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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