anti-CD134 FITC Conjugate

Human CD134 (OX40) (ACT35) is an activation-associated antigen which is predominantly expressed on activated CD4 positive cells.  CD134 antigen is a member of the tumor necrosis factor (TNF) receptor family of molecules and may be involved with regulating T cell-dependent B cell proliferation and differentiation (2).

Isotype: Murine IgG1

Immunogen: Human HUT 102 T cells

Specificity: Antibody BerAct35 recognizes an extracellular epitope of the human CD134 molecule of about 35 kd (1, 3). BerAct35 does not block the interaction between CD134(OX40) and CD252(OX40L). 

Functional Application:  Antibody BerAct35 inhibited perforin mRNA expression in PHA stimulated PBMC (5).

References:

1.  U. Latza, et al, (1994) Eur J Immunol  24: 677-683.

2.  E. Stuber, et al, (1995) Immunity  2: 507-521.

3.  Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 464-465.

4.   Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1157-1160.

5.   Ming Li, Yuanchao Zhang (2005) Cell Mol Immunol 2(6):467-271.

USD $300.00
In cart: 0
= $300.00
Catalog #:
355-040
Form:
FITC
Size:
120 tests
Alternate Name:
OX40, ACT35, CD134
Clone:
BerAct35
Applications:
EIA, FC, FX, IHC, IP(1), WB(1

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

1
Categories:

Downloads