anti-CD105 FITC Conjugate
Isotype: Murine IgG1 kappa
Immunogen: Membrane preparation of human B-lineage leukemia cells
Specificity: Antibody SN6 recognizes an extracellular epitope of the human CD105 homodimer with a molecular weight of about 160 kd. It has been reported to cross react with non human Primate as well as Equine and Porcine(11) CD105.
Functional Application: Antibody SN6 will augment binding of TGF-b1 to CD105 expressing leukemia cells. Antibody SN6 has been used to identify mesenchymal progenitor cell sub populations (8,9,10,13)
References:
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11. G Vilahur, L Badimon, et al. Oct 13, 2014 Toxicol Pathol pii: 0192623314551971.
12. M Vigano, de Girolamo, et al. (Feb 2017) J Exp Orthopaedics 4: 8.
13. M.T. Weickert, KS Gotze, et al. (2021 Mar 15) Sci Rep 11(1): 5944 doi: 10.1038/s41598-021-85122-8.