anti-CD98 FITC Conjugate
Human CD98 (4F2) is a heterodimeric glycoproein expressed on monocytes and activated cells. All cultured human cell lines tested express CD98. CD98 heavy chain mediates adhesion induced activation through integrin signalling (4) .
Isotype: Murine IgG1
Immunogen: Molt 13 T cell line
Specificity: Antibody UM7F8 recognizes the heavy chain of a 125 kd heterodimeric membrane glycoprotein CD98 (1-3 ).
Functional Application: Antibody UM7F8 is comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs (1).
References:
1. AW Friedman, DA Fox, et al. (1994) Cell Immunol 154: 253-263.
2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 280-283.
3. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 531-534.
4. Feral CC, Ginsberg MH, et al. (2005) PNAS USA 102(2): 355-360.