anti-CD98 R-PE Conjugate

Human CD98 (4F2) is a heterodimeric glycoproein expressed on monocytes and activated cells.  All cultured human cell lines tested express CD98.  CD98 heavy chain mediates adhesion induced activation through integrin signalling (4) .

Isotype: Murine IgG1

Immunogen: Molt 13 T cell line

Specificity: Antibody UM7F8 recognizes the heavy chain of a 125 kd heterodimeric membrane glycoprotein CD98 (1-3 ).

Functional Application: Antibody UM7F8 is comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs (1).

References:

1.  AW Friedman, DA Fox, et al. (1994) Cell Immunol  154: 253-263.

2.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 280-283.

3.  Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 531-534.

4.  Feral CC, Ginsberg MH, et al. (2005) PNAS USA 102(2): 355-360.

USD $325.00
In cart: 0
= $325.00
Catalog #:
319-050
Form:
R-PE
Size:
120 tests
Alternate Name:
4F2, LAT1
Clone:
UM7F8
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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