anti-CD86 Biotinylated

Human CD86 (B7-2) is a costimulating ligand for CD28 and CTLA-4.  CD86 is expressed on activated B cells and blood monocytes (3).

Isotype: Murine IgG1

Immunogen: ARH-77 (B-lymphoblastoid cell line)

Specificity: Antibody BU63 recognizes the CD86 molecule of 80 kd (3).

Functional Application: Antibody BU63 blocks MLR and blocks binding of soluble CD152-muIg fusion protein to CD86.

References:

1.  C. Caux, et al, (1994) J Exp Med  180: 1841-1847.

2.  C.B. Thompson, (1995) Cell  81: 979-982.

3.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 703-705.

4.  D. Mauri, et al, (1995) J Immunol  155: 118-127.

USD $275.00
In cart: 0
= $275.00
Catalog #:
307-030
Form:
Biotin
Size:
100 µg
Alternate Name:
B7-2
Clone:
BU63
Applications:
EIA, FC, WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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