anti-CD268(BAFFR) Purified (Preservative-free)

Immunogen: Recombinant human CD268

INFORMATION : Human CD268 (BAFFR, BAFF receptor) is a type I TNF superfamily  receptor  member  #13c.  It is highly specific for  CD257 (BAFF)., which itself does bind to other receptors TACI, and BCMA.  CD268 expressed on B cells and its ligation by CD257 (BAFF) regulates maturation (1).  Antibody ANC268.2 binds to recombinant CD268 (but not CD269) in EIA and native CD268 expressed on Raji cell surface. ANC268.2 has been used to analyze BCP-ALL patient blood (2).

REFERENCES:

1) Thompson, J S, C Ambrose, et al. (2001) Science 293(5537): 2108-2111.  

2) G Fazio, G Cazzaniga, et al. (2017) BJH doi: 10.1111/bjh. 14794   PMID: 28573703