Isotype: Mouse IgG1k
Immunogen: Recombinant human CD268
INFORMATION : Human CD268 (BAFFR, BAFF receptor) is a type I TNF superfamily receptor member #13c. It is highly specific for CD257 (BAFF)., which itself does bind to other receptors TACI, and BCMA. CD268 expressed on B cells and its ligation by CD257 (BAFF) regulates maturation (1). Antibody ANC268.2 binds to recombinant CD268 (but not CD269) in EIA and native CD268 expressed on Raji cell surface. ANC268.2 has been used to analyze BCP-ALL patient blood (2).