anti-CD269(BCMA) Purified (Preservative-free)

Isotype:  Mouse IgG1k

Immunogen: Recombinant human CD269

INFORMATION : Human CD269 (BCMA, B cell maturation antigen) is predominantly expressed by mature B cells and is a type I TNF superfamily  receptor  member (TNFRSF17) .  It is highly specific for its ligand  CD257 (BAFF, Blys).    

Antibody ANC3B1 binds to recombinant CD269 (but not CD268) in EIA and native CD269 expressed on cell surface(2). It blocks binding of recombinant soluble CD257(BAFF)trn-muCD8(cat# 525-020) to recombinant CD269(BCMA)-muIg (cat# 519-020)  in EIA.

REFERENCES:

1) Schneider P., J. Tschopp, et al. J. Exp. Med. 1999, 189(11):1747-1756.

2) T Gantke, M Treder, et al. (Sept 2017) Protein Engineering, Design and Selection 30(9): 673-684. PMID 28981915 DOI: 10.1093/protein/gzx043

USD $235.00
In cart: 0
= $235.00
Catalog #:
269-820
Form:
Pur/PF
Size:
100 µg
Alternate Name:
BCMA, TNFRSF17, B cell maturation factor, CD269
Clone:
ANC3B1
Applications:
EIA, FC (2)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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