anti-CD62E Biotinylated

Human CD62E (E-selectin) is an adhesion molecule expressed on activated endothelium and facilitates recruitment of leukocytes to sights of acute inflammation and immunological events.  CD62E has affinity to Lewisx(1).

Isotype: Murine IgG1

Immunogen: TNF activated HUVEC

Specificity: Antibody HAE-1f  recognizes the lectin domain of CD62E (2).

Functional Application: Antibody HAE-1f blocks the function of CD62E.  It has been used for FACS analysis of circulating Endothelial Microparticles (4).

References:

1.  T.P. Kogan, et al, (1995) J Biol Chem  270: 14047-14055.

2.  L. Tu, et al, (1996) J Immunol 157: 3995-4004.

3.  Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York  (1997) p. 416-419.

4.  AF Tramontano, L Ragolia, et al. (2010) Mediators of Inflammation 2010: 250476  doi:10.1155/2010/250476.

USD $235.00
In cart: 0
= $235.00
Catalog #:
240-030
Form:
Biotin
Size:
100 µg
Alternate Name:
E-selectin, ELAM-1
Clone:
HAE-1f
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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