anti-CD58(LFA-3) Biotinylated

Human CD58 is a cell surface glycoprotein  with wide distribution on hemopoetic cells and functions as an adhesion molecule mediating a costimulatory signal through CD2.  CD58 is attached to the cell surface by either of two forms – transmembrane or GPI.

Isotype: Murine IgG1     

Immunogen:  Human cytotoxic  T cells  

Specificity:  Antibody TS2/9 reacts with both transmembrane and GPI anchored CD58.   

Functional Application:  Antibody TS2/9 will inhibit HLA-DR mediated T cell cytotoxicity (3).

References: 

1.  Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 414-415.

2.  A.R. Arulanandam, et al, (1994) J Exp Med  180:1861-1871. 

3. Vollger LW, Singer KH, et al. (1987) J Immunol 138(2): 358-63.

USD $235.00
In cart: 0
= $235.00
Catalog #:
210-030
Form:
Biotin
Size:
100 µg
Alternate Name:
LFA-3
Clone:
TS2/9
Applications:
Blocking (3), EIA, FC, FPS, WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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