anti-CD57 FITC Conjugate

Human CD57 originally called HNK-1, is a glycoprotein found on 15-20 percent of PBL’s including 60 percent of NK cells and a subset of T cells (1).  The immune regulation role of CD57 positive PBL’s expressing high levels of CD8 is being investigated (2).

Isotype: Murine IgM

Immunogen: Human PBL’s

Specificity: Antibody NK-1 recognizes the CD57 molecule of about 110 kd.

References:

1.   Leukocyte Typing V (S.F. Schlossman, et al, eds.)  Oxford University Press, Oxford  (1995)  p. 1412-1414.

2.  E.C.Y. Wang, et al, (1995) J Immunol 155: 5046-5056.