Human CD57 originally called HNK-1, is a glycoprotein found on 15-20 percent of PBL’s including 60 percent of NK cells and a subset of T cells (1). The immune regulation role of CD57 positive PBL’s expressing high levels of CD8 is being investigated (2).
Isotype: Murine IgM
Immunogen: Human PBL’s
Specificity: Antibody NK-1 recognizes the CD57 molecule of about 110 kd.
1. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford (1995) p. 1412-1414.
2. E.C.Y. Wang, et al, (1995) J Immunol 155: 5046-5056.