anti-CD51 Purified (with Antibiotics)
Human CD51 is an integrin alpha v chain which can associate with five different integrin beta chains to form various adhesion molecules (2). The alpha v beta 3 integrin complex binds vitronectin at the RGD sequence and also can bind to fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen (1).
Isotype: Murine IgG1 kappa
Immunogen: Human ocular melanoma cell line (V+B2)
Specificity:Antibody P2W7 recognizes the alpha 5 molecule of 160 kd.
References:
1. R.O. Hynes, (1992) Cell 69: 11-25.
2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford (1995) p. 1663-1664.