anti-CD51 R-PE Conjugate

Human CD51 is an integrin alpha v chain which can associate with five different integrin beta chains to form various adhesion molecules (2).  The alpha v beta 3 integrin complex binds vitronectin at the RGD sequence and also can bind to fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen (1).

Isotype: Murine IgG1 kappa

Immunogen: Human ocular melanoma cell line (V+B2)

Specificity:Antibody P2W7 recognizes the alpha 5 molecule of 160 kd.

References:

1.  R.O. Hynes, (1992) Cell  69: 11-25.

2.  Leukocyte Typing V (S.F. Schlossman, et al, eds.)  Oxford University Press, Oxford  (1995) p. 1663-1664.

3.  Zhen Fan, Mingjon Zhang, et al.(2018) Nature Communications 9: 2605.  doi: 10.1018/S41467-018-04763-yDO.

USD $275.00
In cart: 0
= $275.00
Catalog #:
202-050
Form:
R-PE
Size:
120 tests
Alternate Name:
vitronectin Receptor
Clone:
P2W7
Applications:
FC(3)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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