anti-CD45R Purified (with Antibiotics)

Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes.  CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments.  CD45 plays an essential role in lymphocyte activation (2).

Isotype: Murine IgM

Immunogen: Peripheral blood mononuclear cells

Specificity: Antibody 351C5 recognizes the CD45R  isoforms of about 200-220 kd (1).

References:

1.  L.J. Murray, et al, (1985) Clin Exp Immunol  59: 315-326.

2.  I.S. Trowbridge & M.L. Thomas, (1994) Annu Rev Immunol  12: 85-116.

3.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 394-397.

4.  D. Leitenberg, et al, (1996) J Exp Med  183: 249-259

USD $175.00
In cart: 0
= $175.00
Catalog #:
195-020
Form:
Pur/WA
Size:
100 µg
Clone:
351C5
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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