Human CD41 is a member of a major platelet transmembrane glycoprotein complex (CD41/CD61) which mediates platelet aggregation and adhesion by serving as the receptor for fibrinogen and von Willebrand factor, fibronectin and vitronectin.
Isotype: Murine IgG1
Immunogen: Human PBL
Specificity: Antibody 96.2C1 recognizes the CD41a of about 140 kd (1).
Functional Application: Antibody 96.2C1 has been used for flow cytometry to analyze circulating Endothelial Microparticles (3).
1. Leukocyte Typing III (A.J. McMichael, et al, eds.) Oxford University Press, Oxford, (1987) p. 744.
2. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 643-648.