anti-CD35 FITC Conjugate

Human CD35 binds complement components C3b , C4b, and iC3b and is expressed on erythrocytes, B cells, monocytes, granulocytes and folicular dendritic cells and on subsets of thymocytes (3).  CD35 on erythrocytes mediates clearance of immune complexes.

Isotype: Murine IgG1

Immunogen: Human monocytes

Specificity: Antibody E11 recognizes a complement receptor 1 (CD35) molecule of about 220 kd (1, 2).  It is crossreactive with cynomolgus monkey CD35 (5).

References:

1.  N. Hogg, et al, (1984) Eur J Immunol  14: 236-243.

2.  Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 829-830.

3.  C.C. Delibrias, et al, (1994) Eur J Immunol  24: 2784-2788.

4.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 871-874.

5. Yoshino N, Honda M, et al. (2000) Exp Anim 49(2):97-110.

6. Barber, K.E., Ghebrehiwet, B., Yin, W. et al. (2017) Cel. Mol. Bioeng. 10: 124. 

USD $235.00
In cart: 0
= $235.00
Catalog #:
184-040
Form:
FITC
Size:
120 tests
Alternate Name:
CR1, C3bR
Clone:
E11
Applications:
EIA(6), FC, WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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