anti-CD31 Biotinylated

Human CD31 is an adhesion molecule expressed on platelets, endothelial cells, leukocytes and their bone marrow precursors.  CD31 plays a role in homophilic adhesion and heterophilic transendothelial migration (3).

Isotype: Murine IgG1

Immunogen: Stimulated human leukocytes

Specificity: Antibody 158-2B3 reacts with domain 1 of CD31 (1).

Functional Application: Antibody 158-2B3 blocks homophilic interaction and heterophilic transendothelial migration(1).  It has been used for FACS analysis of circulating Endothelial Microparticles (4).

References:

1.  Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 362-372.

2.  P.J. Newman, (1997) J Clin Invest  99: 3-10.

3.  K.L. Yong, et al, (1998) Blood   91: 1196-1205.

4.  AF Tramontano, L Ragolia, et al. (2010) Mediators of Inflammation 2010: 250476  doi:10.1155/2010/250476.

5. I Soaita, W Yin, D A Rubenstein (Jan 2017) Platelets http://dx.doi.org/10.1080/09537104.2016.1260703

USD $210.00
In cart: 0
= $210.00
Catalog #:
180-030
Form:
Biotin
Size:
100 µg
Alternate Name:
PECAM-1, 158.2B3
Clone:
158-2B3
Applications:
FC(5)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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