anti-CD26 Biotinylated

Human CD26 is a T cell activation antigen which can be associated with costimulation (1).  The significance of the dipeptidyl peptidase IV activity remains unknown.  Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role (2). Soluble CD26 serum levels are predictive for colorectal cancer (3). CD26 is expressed at high levels on CD4+ Th17 T cells (4).  Anti-CD26 mAb has been used to identify T cell-produced virion in CSF of HIV patients (5).

Isotype: Murine IgG2b

Immunogen: Human T cell clone

Specificity: Antibody 202.36 reacts with the type II membrane protein CD26.

References:

1.)  Leukocyte Typing V (S.F. Schlossman, et al, eds.)  Oxford University Press, Oxford  (1995) p. 1105-1114.

2.)  R.P. Dong, et al, (1996) J Immunol  156: 1349-1355.

3.)   OJ Cordero,  M Páez de la Cadena, et al, (2000) British Journal of Cancer 83(9), 1139–1146.

4.) Bengsch B, R Thimme, et al, (2012) J Immunol 188(11): 5438-5447.

5.) G Lustig, A Sigal, et al. (Sep 2021) PLoS Pathog 17(9): e1009871   doi: 10.1371/journal.ppath.1009871.eCollection 2021 Sep.

USD $210.00
In cart: 0
= $210.00
Catalog #:
175-030
Form:
Biotin
Size:
100 µg
Alternate Name:
dipeptidyl peptidase IV, DPPIV
Clone:
202.36
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

1
Categories:

Downloads