anti-CD21 FITC Conjugate

Human CD21 is a receptor for complement fragments C3d, C3dg or ic3D (1, 5) and also EBV (4).  CD21 is also a ligand for CD23 and plays a role in IgE synthesis (3).

Isotype: Murine IgG1

Immunogen: Human HFB-1 cell line

Specificity: Antibody BU33 recognizes the CD21 molecule of about 145 kd (1).  BU33 has been shown to bind to Equine B cells, suggesting cross reactivity (7).

Functional Application: Antibody BU33 inhibits the CD21 – CD23 interaction (2, 6, 8).

References:

1.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995)  p. 516-523.

2.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 535-538.

3.  J.Y. Bonnefoy, et al, (1995) Intl Archiv Allergy Immunol  107: 40-42.

4.  A.D. Beaulieu, et al, (1995) Blood  86: 2789-2798.

5.  H. Molina, et al, (1995) J Immunol  154: 5426-5435.

6.  S Henchoz, J Y Bonnefoy, et al. (1994) Immunology 81(2): 285-290.

7.  S. Mayall, Hamblin A.S., et al. (2001) J Comp Pathol 124(1): 83-87.

8.  S Henchoz, J Y Bonnefoy, et al. (1996) Immunolgy 88: 35-39.

USD $235.00
In cart: 0
= $235.00
Catalog #:
170-040
Form:
FITC
Size:
120 tests
Alternate Name:
CR2
Clone:
BU33
Applications:
FC, WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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