anti-human Lambda R-PE Conjugate

Human immunoglobulins are glycoproteins composed of two disulfide-bonded heavy (H) chain subunits, each of which is linked by interchain disulfide bonds to a light (L) chain forming a tetramolecular complex. There are five classes of immunoglobulins, designated IgG, IgA, IgM, IgD and IgE, which are defined by differences in the constant region of H chains. L chains are divided into kappa or lambda classifications based on structural antigenic differences. All classes of immunoglobulins have been found on the cell surface of B lymphocytes where they function as antigen receptors to elicit antigen-dependent proliferation and secretion of antigen specific soluble circulating antibodies.

Isotype: Murine IgG1

Immunogen: Human Ig

Specificity: Antibody ICO106 recognizes cell surface lambda chain on B cells

References:

1. Basic and Clinical Immunology, Seventh edition (D. P. Sites & A. I. Terr, eds.) Appleton & Lange., Norwalk, CT (1991).

USD $275.00
In cart: 0
= $275.00
Catalog #:
138-050
Form:
R-PE
Size:
120 tests
Alternate Name:
Lambda Light chain, Light Chain, Lambda
Clone:
ICO-106
Categories:

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