anti-TCR Vβ3 R-PE Conjugate

Human T cell receptor (TCR) is a T cell surface expressed heterodimer of alpha/beta or gamma/delta chains.  TCR’s recognize antigen peptides bound to MHC molecules forming the basis of antigen specific response by T cells (3, 4).

Isotype: Murine IgG2a lambda

Immunogen: Human HA1.7 TCR beta chain expressed on transgenic mouse cells

Specificity: Antibody JOVI-3 is specific for the human V beta 3 TCR gene product and reacts with 1-10 of T cells in normal human blood (1, 5).

Functional Application: Antibody JOVI-3 is mitogenic for T cells expressing TCR V beta 3.

References:

1.  J.L. Viney, et al, (1992) Hybridoma 11: 701-713.

2.  A. Weiss, (1993) Cell 73: 209-212.

3.  M.M. Daris, (1995) Nature 375: 104.

4.  S. Valitutti, et al, (1995) Nature 375: 148-151.

5. Y Watanabe, K Sugamura, et al (2009) Int Immunol 21(7): 843-858. PMID: 19515798

USD $425.00
In cart: 0
= $425.00
Catalog #:
102-050
Form:
R-PE
Size:
120 tests

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