anti-TCR Vβ3 R-PE Conjugate

Human T cell receptor (TCR) is a T cell surface expressed heterodimer of alpha/beta or gamma/delta chains.  TCR’s recognize antigen peptides bound to MHC molecules forming the basis of antigen specific response by T cells (3, 4).

Isotype: Murine IgG2a lambda

Immunogen: Human HA1.7 TCR beta chain expressed on transgenic mouse cells

Specificity: Antibody JOVI-3 is specific for the human V beta 3 TCR gene product and reacts with 1-10 of T cells in normal human blood (1, 5).

Functional Application: Antibody JOVI-3 is mitogenic for T cells expressing TCR V beta 3.

References:

1.  J.L. Viney, et al, (1992) Hybridoma 11: 701-713.

2.  A. Weiss, (1993) Cell 73: 209-212.

3.  M.M. Daris, (1995) Nature 375: 104.

4.  S. Valitutti, et al, (1995) Nature 375: 148-151.

5. Y Watanabe, K Sugamura, et al (2009) Int Immunol 21(7): 843-858. PMID: 19515798

USD $450.00
In cart: 0
= $450.00
Catalog #:
102-050
Form:
R-PE
Size:
120 tests
Clone:
Jovi-3
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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