“CD58/CD2 Is the Primary Costimulatory Pathway in Human CD28−CD8+ T Cells” J Leitner, P Steinberger, et al. (2015) J Immunol 195(2): 477-87. PMID: 26041540. Related Ancell Research Products anti-CD2 mAb (clone 1E7E8 UMCD2) anti-CD58(LFA-3) (clone TS2/9)
“Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell–Mediated Suppression in the Context of Autoimmunity” S A Basdeo, J M Fletcher, et al. (2015) J Immunol 195(2): 528-540. PMID 26062995. Ancell anti-Human CD161 antibody Products
Matched pair of anti-human CD155(PVR) mAbs for Flow Cytometry and EIA Clone ANC2B2 Purified 255-020 Biotinylated 255-030 Clone ANC6A3 Purified 350-020 Biotinylated 350-030 Recombinant Soluble Poliovirus Receptor CD155-muIg Binds to Ligand(s) Upregulated on Stimulated Human Peripheral Blood Lymphoid Cells Recombinant Human CD155(PVR)-muIg Purified CD155-muIg 555-020 Biotinylated
New CD155(PVR) Products Available! Read More »
“Analysis of Programmed Death-1 in Patients with Psoriatic Arthritis” M Peled, A Mor, et al. Feb 10 2015 Inflammation PMID: 25663558 Related Ancell Research Products Human CD279 (PD-1) Products (mAbs and Recombinant Proteins) Superagonist anti-human CD28 mAb anti-human CD3 mAb
“Nitric Ooxide Donors Iincrease PVR/CD155 DNAM-1 Ligand Expression in Multiple Myeloma Cell: Role of DNA Damage Response Activation” Cinzia Fionda, Marco Cippitelli, et al. (2015) BMC Cancer 15(1): 17 PMID: 25609078 Ancell human CD155 recombinant protein and monoclonal antibody products available soon!
“Semaforin Sema4D in the Immune System in Mulple Sclerosis.” E.M. Kulkina, I.V. Nekrasova, et al. (June 2014) Bull Exp Biol Med 157(2): 234-237. PMID 24952493 “Expression of Semaphorin CD100 on Peripheral Blood T-Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis” T.N. Trushnikova, I.V. Nekrasova, et al. (Oct 2013) Multiple Sclerosis 113(10 pt 2): 47-51. PMID 24300815
CD100 (Sema4D) is a Useful Marker for Multiple Sclerosis Read More »
The Macrophage Mediator, Maresin-1, is derived from the Omega-3 Fatty acid DHA. In a murine asthma model exogenously added Maresin-1 augmented T regulatory cells expansion and reduced lung inflammation with lower detectable levels of IL-5 and IL-13 “Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of
Maresin-1 is a Promising Candidate for Asthma Therapy Read More »
BAFF levels in bronchoalveolar fluid are higher in allergic vs tolerant mice, and increase with repeated immunization. Blocking BAFF interactions may prove an effective therapeutic intervention for chronic respiratory diseases. “Investigating the Role of BAFF in Murine Models of Allergic Asthma” A Lorenz, A Meyer-Bahlburg, et al. (2014) European Respiratory Journal 44(Suppl 58): 4213.
BAFF(CD257) levels correlate with severity of Asthma Read More »
In a mouse adoptive adoptive transfer T cell exhaustion model improved T cell proliferation was observed when agonistic antibodies against CD27 and CD134 were included with the CD274 blockade. “OX40- and CD27-Mediated Costimulation Synergizes with Anti-PD-L1 Blockade by Forcing Exhausted CD8+ T Cells to Exit Quiescence” Sarah L. Buchan, Aymen Al-Shamkhani, Ronjon Chakraverty, et al.
oxLDL-IC pathology was mediated by CD36 and CD64 receptors on retinal pericytes. “Immune complex formation in human diabetic retina enhances toxicity of oxidized LDL towards retinal capillary pericytes.” D Fu, T J Lyons, et al. (May, 2014) J Lipid Res 55: 860-869. PMID: 24616481 Ancell reagents were used in this study to selectively block IC
