“Analysis of Programmed Death-1 in Patients with Psoriatic Arthritis” M Peled, A Mor, et al. Feb 10 2015 Inflammation PMID: 25663558     Related Ancell Research Products     Human CD279 (PD-1) Products (mAbs and Recombinant Proteins)   Superagonist anti-human CD28 mAb   anti-human CD3 mAb

  “Nitric Ooxide Donors Iincrease PVR/CD155 DNAM-1 Ligand Expression in Multiple Myeloma Cell: Role of DNA Damage Response Activation”  Cinzia Fionda, Marco Cippitelli, et al. (2015) BMC Cancer 15(1): 17 PMID: 25609078    Ancell human CD155 recombinant protein and monoclonal antibody products available soon!

“Semaforin Sema4D in the Immune System in Mulple Sclerosis.” E.M. Kulkina, I.V. Nekrasova, et al. (June 2014) Bull Exp Biol Med 157(2): 234-237. PMID 24952493 “Expression of Semaphorin CD100 on Peripheral Blood T-Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis”  T.N. Trushnikova, I.V. Nekrasova, et al. (Oct 2013) Multiple Sclerosis 113(10 pt 2): 47-51. PMID 24300815

The Macrophage Mediator, Maresin-1, is derived from the Omega-3 Fatty acid DHA. In a murine asthma model exogenously added Maresin-1 augmented T regulatory cells expansion and reduced lung inflammation with lower detectable levels of IL-5 and IL-13   “Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of

BAFF levels in bronchoalveolar fluid are higher in allergic vs tolerant mice, and increase with repeated immunization. Blocking BAFF interactions may prove an effective therapeutic intervention for chronic respiratory diseases. “Investigating the Role of BAFF in Murine Models of Allergic Asthma” A Lorenz, A Meyer-Bahlburg, et al. (2014) European Respiratory Journal 44(Suppl 58): 4213.  

In a mouse adoptive adoptive transfer T cell exhaustion model improved T cell proliferation was observed when agonistic antibodies against CD27 and CD134 were included with the CD274 blockade.  “OX40- and CD27-Mediated Costimulation Synergizes with Anti-PD-L1 Blockade by Forcing Exhausted CD8+ T Cells to Exit Quiescence” Sarah L. Buchan, Aymen Al-Shamkhani, Ronjon Chakraverty, et al. 

oxLDL-IC pathology was mediated by CD36 and CD64 receptors on retinal pericytes.  “Immune complex formation in human diabetic retina enhances toxicity of oxidized LDL towards retinal capillary pericytes.” D Fu, T J Lyons, et al. (May, 2014) J Lipid Res 55: 860-869.  PMID: 24616481 Ancell reagents were used in this study to selectively block IC

A matched pair of EIA antibodies to detect CD272(BTLA)  

Autumn Immunolgy Conference in Chicago is November 21st through 24th.  Visit our booth!

Level of CD4+CD39+/CD161+ T cell sub population in muscosal membranes and peripheral blood correlate to severity of Crohns Disease.  “CD39 and CD161 Modulate Th17 Responses in Crohn’s Disease” A Bai, S C Robson, et al. (2014) J Immunol 193(7): 3366-3377. PMID:25172498 Relevant Ancell antibodies and conjugates anti-human CD4 anti-human CD39 anti-human CD161