anti-Mouse CD4/DyLight350 conjugate

Improved multi-color staining of Mouse tissues Anti-Mouse CD4 (clone GK1.5)/DyLight350*  conjugate now available!   Catalog #704-350 DyLight350* is excitable by Near-UV laser Amax 353, and emits in the blue range, Emax 432nm. Look for more DyLight350 conjugates available soon!

CD134(OX40) Signaling Mechanism Elucidated

Engagement of CD134(OX40) by its Ligand (CD252) induces an intracellular signaling complex which  includes PKB, and PI3K, and requires TRAF2. Takanori S, H Choi, M Croft. (2011) J Immunol 186(6):3547-3555.   Ancell Products: Recombinant human CD134-muIg Fusion protein Recombinant human CD252(OX40)-muCD8 Monoclonal anti-human CD134(OX40) Monoclonal anti-human CD252(OX40L)  

CD28 Superagonist protects against Rheumatoid Arthritis mediated bone destruction

In mice, use of CD28 superagonist has been shown to increase the % of Treg cells, and protect from Rheumatoid Arthritis mediated bone destruction.Marlo M Zaiss, Jean-Pierre David, et al. (2010) J Immunol 184: 7238-7246. Ancell anti-CD28 antibody clone ANC28.1/5D10 has been characterized as a superagonist. This mAb has been found to be capable of stimulating …

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