Humanized Mice Reviewed
Authors review utilization of various types of humanized mice to study human immunological mechanisms. Challenges include engineering humanized populations of Neutrophils, Red Blood Cells, Hepatocytes, and resident Skin macrophages. They cite and recommend multi-omic canonical correlations of human vs humanized mouse biomarkers to assess the utility of these technologies. “Engineering Mice to Study Human Immunity” […]
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