Blocking CD40-CD154 interaction with an antagonistic anti-CD40 mAb alleviates SLE symptoms in mice.

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“Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus”

Stuart J, Stephen H Clarke, et al.  July 1, 2019 Journal of Immunology 203(1): 58-75.  Doi: htpps://doi.org.10.4049/jimmunol.1900043.

 

Relevant Ancell Products

anti-human CD40 mAb

Recombinant human CD40-muIg

Recombinant human CD154-muCD8