The CD2 – CD58(LFA3) interaction is the main co stimulatory pathway for CD28- Effector T cellsBy room34 / July 27, 2015 “CD58/CD2 Is the Primary Costimulatory Pathway in Human CD28−CD8+ T Cells” J Leitner, P Steinberger, et al. (2015) J Immunol 195(2): 477-87. PMID: 26041540. Related Ancell Research Products anti-CD2 mAb (clone 1E7E8 UMCD2) anti-CD58(LFA-3) (clone TS2/9)