anti-mouse CD3ε R-PE Conjugate

Antibody 145-2C11binds to an extracellular epitope of the 25 kd CD3e molecule present on murine T cells (1).  CD3 molecules associate with T cell Receptors and provide intracellular signaling mechanism.  Cross linking cell surface CD3 with soluble or immobilized 145-2C11 can activate this mechanism(2).

Isotype:  Hamster IgG

Immunogen:  Mouse BM10-37 T cell membrane prep

References:

1) O Leo, J A Bluestone, et al. (1987) PNAS USA 84(5): 1374-1378. 

2) L E Samelson, J A Bluestone, et al. (1987) J Immunol 139(8): 2708-2714.

USD $275.00
In cart: 0
= $275.00
Catalog #:
703-050
Form:
R-PE
Size:
120 tests
Clone:
145-2C11
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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