CD127-muIg Purified (Preservative-free)

CD127 (IL-7Ra) is the specific receptor component for the cytokine Interleukin -7 (IL-7).  It is found on a wide variety of hematopoietic cell types including B cell precursors, and the majority of T cells.  Its expression levels are decreased on T cells following activation.   CD127 can dimerize with CD132(IL-2Rg) to form a high affinity IL-7 receptor (1).  CD127 engagement is necessary for T cell development in humans (2).

Isotype: Murine IgG1 kappa

Immunogen: Recombinant human CD127

Specificity:  Antibody ANC8F2 recognizes an extracellular epitope of recombinant and native CD127 in FACS and Enzyme Immunoassay

References:  .

1) Noguchi, M. et al., 1993, Science 262:1877.

2) Pribyl, J.A. and T.W. LeBien, 1996, Proc. Natl. Acad. Sci. 93:10348.

3) Goodwin RG, Friend D, Ziegler SF, et al. Cell. 1990;60:941.

USD $325.00
In cart: 0
= $325.00
Catalog #:
539-820
Form:
Pur/PF
Size:
25 µg
Alternate Name:
IL-7R
Applications:
EIA

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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