CD270(HVEM)-muIg Purified (Preservative-free)

Human CD270 (Herpes Virus Entry Mediator, HVEM, TNFRSF14, ATAR, LIGHTR, TR2 ) is a 36kd type I membrane protein that has been found on a broad range of lymphoid tissues.  Its ligands include the TNF Ligand family members LTalpha and LIGHT, and the CD28/Ig Superfamily member BTLA(2).

Molecular Structure: A soluble fusion protein consisting of the extracellular (187aa) domain of mature human HVEM fused to murine IgG2a Fc (233aa) with a predicted non glycosylated molecular    weight of 46.4 kd.

Transfectant Cell Line: CHO 

Functional Application: Human CD270-muIg fusion protein binds to recombinant BTLA and LIGHT in EIA (3).

References:

1) Hsu H, et al. (1997) J Biol Chem 272:13471. 

2) Gonzalez LC, et al. (2005) PNAS 102(4): 1116-1121.

3) Guifang Cai, Gordon J Freeman, et al. (2008) Nature Immunol 9: 176 – 185.

USD $325.00
In cart: 0
= $325.00
Catalog #:
531-820
Form:
Pur/PF
Size:
25 µg
Applications:
EIA

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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