DR3-muIg Biotinylated

Human DR3 (TRAMP, LARD) was redesignated TNF receptor superfamily member 25. TL1A is a ligand which can induce apoptosis through a cytoplasmic death domain similar to the CD178-CD95 (FasL-Fas) interaction.  Alternatively, engagement of DR3 on T cells can synergize with other activating signals to enhance IFN g production.

Recombinant DR3-muIg binds to recombinant TL1A in EIA.

Molecular Structure:   A soluble fusion protein combining the extracellular (150aa) domain of human DR3 and murine IgG2a Fc and hinge region (233aa), with a predicted monomeric molecular weight of 42.9 kd. 

N-teminal sequence: (27) GTRSP

Transfectant Cell Line:   CHO  

References:

(1) A Kaptein, et al. (2000) FEBS Lett 485:135.

(2) T Migone, et al. (2002) Immunity 16:479.

(3) S Targin, et al. (2004) 172: 7002.

USD $425.00
In cart: 0
= $425.00
Catalog #:
528-030
Form:
Biotin
Size:
25 µg
Alternate Name:
TRAMP, LARD, TNFRSF25
Applications:
EIA

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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