anti-CD127 Biotinylated

CD127 (IL-7Ra) is the specific receptor component for the cytokine Interleukin -7 (IL-7).  It is found on a wide variety of hematopoietic cell types including B cell precursors, and the majority of T cells.  Its expression levels are decreased on T cells following activation.   CD127 can dimerize with CD132(IL-2Rg) to form a high affinity IL-7 receptor (1).  CD127 engagement is necessary for T cell development in humans (2).

Isotype: Murine IgG1 kappa

Immunogen: Recombinant human CD127

Specificity: Antibody ANC8F2 recognizes an extracellular epitope of human recombinant and native CD127 in FACS and Enzyme Immunoassay.

References: 

1)  Noguchi, M. et al., 1993, Science 262:1877.

2)  Pribyl, J.A. and T.W. LeBien, 1996, Proc. Natl. Acad. Sci. 93:10348. 

3)  Goodwin RG, Friend D, Ziegler SF, et al. Cell. 1990;60:941.

USD $300.00
In cart: 0
= $300.00
Catalog #:
348-030
Form:
Biotin
Size:
100 µg
Alternate Name:
IL-7Rα
Clone:
ANC8F2
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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