anti-CD122 Purified (with Antibiotics)

Human CD122 (IL-2 R beta) associates with CD25 (IL-2R alpha) to form a high affinity receptor for IL-2 and is expressed on activated T cells, B cells and monocytes (3).  The cytoplasmic domain of CD122 is involved with signal transduction (2).

Isotype: Murine IgG2a kappa

Immunogen: YT-1 acute human leukemia cells

Specificity: Antibody 9A2 is specific for the 75 kd b subunit CD122 of the human high affinity interleukin-2 receptor.

Functional Application: Antibody 9A2 (DU-2) inhibits binding of IL-2 to IL-2R beta (CD122) (1).

References:

1.  M.R. Fung, et al, (1991) J Immunol  147: 1253-1260.

2.  M.A. Goldsmith, et al, (1994) J Biol Chem  269: 14698-14704.

3.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1858.

4. Yamaoka K, T Hiroi, et al.(May 2012) Genes to Cells 17: 611-618.  DOI: 10.1111/j.1365-2443.2012.01610.x

USD $175.00
In cart: 0
= $175.00
Catalog #:
343-020
Form:
Pur/WA
Size:
100 µg
Alternate Name:
IL-2Rβ
Clone:
9A2
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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