anti-CD104 R-PE Conjugate

Human CD104 (beta 4 integrin) associates with the alpha 6 integrin chain and binds to laminin and epiligrin and likely has cell-cell adhesion functions.  CD104 is involved in signal transduction (4).

Isotype: Murine IgG2a

Immunogen: UM-SCC-1, human squamous cell carcinoma

Specificity: Antibody UMA9 recognizes an extracellular epitope of the CD104 molecule of about 205 kd (1, 3).

Functional Application: Partially blocks laminin binding.

References:

1.  K.A. Kimmel & T.E. Carey, (1986) Cancer Res  46: 3614-3623.

2.  C VanWaes, et al, (1991) Cancer Res  51: 2395-2402.

3.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1655-1663, 1667-1668.

4.  F. Mainiero, et al, (1995) EMBO J  14: 4470-4481.

5.  S Tyagi, AR Ahmed, et al. (1996) PNAS 93(25): 14714-14719. PMID: 8962120

USD $325.00
In cart: 0
= $325.00
Catalog #:
325-050
Form:
R-PE
Size:
120 tests
Alternate Name:
Integrinβ4
Clone:
UMA9
Applications:
FC, WB(5)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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