anti-CD79b R-PE Conjugate

Human CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta) which associates with B cell antigen receptor Iga chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg) (3).  The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer transduces signals. chain (CD79b) which has a molecular weight of approximately 38 kd (1,4).Analysis of CD79b expression is useful in diagnosis of B cell lymphoproliferative disorders (5).

Isotype: Murine IgG1kappa

Immunogen: Membrane preparation of human B prolymphocytic leukemia cells

Specificity: Antibody SN8 recognizes the extracellular part of the BCR complex beta

Functional Application: Antibody SN8 is able to induce signal transduction in B cells. 

References:

1.  M. Okazaki, et al, (1993) Blood 81: 84-94.

2.  S. Vasile, et al, (1994) Mol Immunol 31: 419-427.

3.  A.L. DeFranco, et al, (1994) Chem Immunol  59: 156-172.

4.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 667-675, 677-681.

5.  McCarron KF, Hsi ED, et al. (2000) Am J Clin Pathol 113:805-813.

USD $350.00
In cart: 0
= $350.00
Catalog #:
301-050
Form:
R-PE
Size:
120 tests
Alternate Name:
BCR-IGβ
Clone:
SN8/3A2-2E7
Applications:
FC, WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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