anti-CD273(PD-L2) FITC Conjugate

CD273 (B7-DC, PD-L2, Programmed Death Ligand 2) is a 25 kd member of the B7 family and is expressed mainly on a sub set of Dendritic cells.  When engaged it has a stimulatory effect on the expressing DC, and delivers a down regulatory signal to cells expressing its counter receptor, CD279(PD-1).  The interaction of CD273(B7-DC) and CD274(B7-H1) with their receptor, CD279(PD-1) is an important component of immune regulation.

Isotype: Murine IgG2a Kappa

Immunogen: Recombinant  human CD273(B7-DC)

Specificity:  Antibody ANC8D12 binds to recombinant CD273 and cell surface CD273 expressed on monocyte derived Dendritic cells (moDC), and blocks binding of recombinant CD279 to CD273 in EIA and FACS.

USD $325.00
In cart: 0
= $325.00
Catalog #:
273-040
Form:
FITC
Size:
120 tests
Alternate Name:
B7-DC, PD-L2, Programmed Death Ligand 2
Clone:
ANC8D12
Applications:
Blocking, EIA, FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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